Glossary · Molecule

ISO E Super / Molecule 01

ISO E Super is a synthetic woody-cedar aroma chemical with a semi-transparent, skin-close character; marketed as Molecule 01 by Escentric Molecules (2006), it became one of the most discussed synthetic molecules in niche perfumery.

Definition

ISO E Super was developed by IFF (International Flavors & Fragrances) in the 1970s. It generates a woody, cedar, smoky, and slightly spicy impression that is difficult to perceive at low concentrations: many wearers experience it as a skin-amplifying presence rather than a distinct note. Geza Schoen's Molecule 01 (Escentric Molecules, 2006) consists of ISO E Super in a carrier, making it the purest commercial expression of the molecule.

This quality, sometimes described informally as skin-amplifying or presence-building by the community, is a sensory phenomenon: the molecule activates specific receptors at concentrations where it reads as ambient rather than applied.

In niche perfumery

ISO E Super appears as a supporting material in hundreds of niche and mainstream compositions, contributing seamless woody depth and diffusion. At high concentrations, as in Andy Tauer's L'Air du Désert Marocain, it reads as a dry desert-air accord. Related molecules from the same structural family include Iso Gamma Super (Givaudan) and Timberol (Givaudan), each offering different facets of the woody spectrum.

Sources

Published on 27 May 2026 · Updated on 27 May 2026 · Author: Sabrina Carlier · Osmetheca.